Wednesday, July 1, 2015

Depo Provera and Circumcision: Violence Against Women Masquerading as Research

Although there are plenty of instances of institutionally sanctioned violence against women, this blog post is about two very prominent instances: mass male circumcision programs [*Greg Boyle, cited below; one of the most up to date publications on the subject, which cites many of the seminal works] and the aggressive promotion of the dangerous injectible contraceptive, Depo Provera (DMPA).
Why are mass male circumcision (MMC) programs instances of violence against women? Well, three trials of MMC were carried out to show that it reduced female to male transmission of HIV. They were show trials, with the entire process monitored to ensure that it gave the results that the researchers wanted. These trials have been cited countless times by popular and academic publications.
Less frequently cited was a single trial of MMC that was intended to show that it reduced male to female transmission of HIV. None of these four trials were independent of each other and the female to male trials produced suspiciously similar results, despite taking place in different countries, with ostensibly different teams. But the single male to female trial showed the opposite to what the researchers wanted: circumcision increased HIV transmission, considerably.
During all four of the trials, male participants were not required to inform their partner if they were found to be HIV positive, or if they became infected during the trial. If there had been any ethical oversight, those refusing to inform their partner would have been excluded from the trial. This is what would have happened in western countries, including the one that funded the research, the US.
Given that many women and men believe that circumcision protects a man from HIV, these MMC programs are giving HIV positive men the means to have possibly unprotected sex with HIV negative women. Many women and men were infected with HIV during the four show trials and almost all of those infections could have been avoided. How participants became infected during the trials has never been investigated, which is not only unethical, but also renders the trials useless.
Despite Depo Provera use substantially increasing the risk of HIV positive women infecting their sexual partners, and the risk of HIV positive men infecting women using the deadly contraceptive, this is the favored contraceptive method for many of the biggest NGOs (many of the biggest NGOs are engaged in population control of some kind). Therefore, its use is far more common in poor countries (especially among sex workers) and among non-white populations in rich countries.
These two instances of violence against women (and men) are funded by the likes of CDC, UNAIDS and the Gates Foundation. Many research papers extolling the virtues of MMC and Depo Provera are paid for by such institutions, copiously cited by them in publications, and constantly wheeled out as examples of successful global health programs. Yet, they are both responsible for countless numbers of avoidable HIV infections.
There is currently a lot of institutional maundering about violence against women and certain instances of it, but some of these same institutions are taking part in the perpetration of it; they are funding it, making money and careers out of it, promoting themselves and their activities on the back of what is entirely unethical. Why do Institutional Review Boards, peer reviewers and academics, donors and others seem happy to ignore these travesties? Who is it that decides that this is all OK, when it clearly is not?
Why are these not considered to be unethical: aggressively promoting the use of a dangerous medication, and an invasive operation that will neither protect men nor women? Is it because those promoting them are making a lot of money out of them, because the victims are mostly poor, non-white people, because the research and programs take place in poor countries, because ethics is nice in principle but too expensive in practice...? Or all of the above and more?
* Boyle, G. J. (2013). Critique of African RCTs into male circumcision and HIV sexual transmission. In G. C. Denniston et al. (Eds.), Genital cutting: Protecting children from medical, cultural, and religious infringements. Dordrecht, The Netherlands: Springer Science+Business Media doi: 10.1007/978-94-007-6407-1_15


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